Over the last four years, I’ve taken two courses of BEG spray – got re-infected after the initial treatment. I herxed mildly (flu symptoms) about three days after starting the spray and it lasted a few days. The spray did sting a bit at first (keep in the refrigerator to reduce stinging) and my nose was very runny the entire time – the result of the biofilm breaking down . Also, there was a slight increase in the ringing in my ears during treatment and near the end of the six weeks I was hit with a wall of super intense joint and muscle pain. I attributed the pain to toxins released by an excess of “bad” microbes (excess yeast and fungi) resulting from the killing off bacteria in my gut with the antibiotics.
In rabbits, fetal weight reduction and cleft palate were observed at a fluticasone propionate dose approximately times the MRHDID for adults (on a mg/m² basis at a maternal subcutaneous dose of 4 mcg/kg/day). However, no teratogenic effects were reported at fluticasone propionate doses up to approximately 20 times the MRHDID for adults (on a mg/m² basis at a maternal oral dose up to 300 mcg/kg/day). No fluticasone propionate was detected in the plasma in this study, consistent with the established low bioavailability following oral administration [see CLINICAL PHARMACOLOGY ].
This press release contains forward looking statements. Forward looking statements include statements about our future plans and other potential future events and may be indicated by words such as, “anticipate,” “plan,” “expect,” “aim” or other similar words, including the expected launch of XHANCE in the second quarter of 2018. While these forward-looking statements represent our current judgment on what the future holds, they are subject to risks and uncertainties that could cause actual results to differ materially. You are cautioned not to place undue reliance on these forward-looking statements, which reflect our opinions only as of the date of this press release (September 18, 2017). We are not obligating ourselves to revise or publicly release the results of any revision to these forward looking statements in light of new information or future events.