Steroid effects on mental health

Cushing's syndrome relates to the multi-organ over exposure of iatrogenic or endogenous corticosteroid and is associated with a variety of psychiatric and psychological disturbances. In one study examining 43 patients before and after treatment for Cushing's psychopathology was observed in a considerable number. Only 8 patients of 43 with active Cushing's syndrome (19%) were without psychiatric symptoms. Psychiatric diagnoses included: neurotic depression in 20 (46%), possible neurotic depression in 1 (2%), reactive depression in 6 (14%), and non-specific neurotic symptoms in 8 (19%). Psychoses were suspected in 3 of the patients who were depressed, but none of the 43 patients with active Cushing's syndrome had a definite diagnosis of Schizophrenia, Mania, Obsessive Compulsive Disorder or Generalised Anxiety Disorder.

Corticosteroid myopathy presents as weakness and wasting of the proximal limb and girdle muscles and is generally reversible following cessation of therapy.

Corticosteroids inhibit intestinal calcium absorption and increase urinary calcium excretion leading to bone resorption and bone loss. Bone loss of 3% over one year has been demonstrated with prednisolone 10 mg per day. Postmenopausal females are particularly at risk for loss of bone density. Sixteen percent of elderly patients treated with corticosteroids for 5 years may experience vertebral compression fractures. One author reported measurable bone loss over two years in women on concomitant therapy with prednisolone mg per day and tamoxifen. [ Ref ]

Again, as with estrone, results with testosterone propionate were not always so positive. In 1939, the Council of Pharmacy and Chemistry of the American Medical Association refused to accept testosterone for New and Nonofficial Remedies stating, ‘the involutional melancholia of males, for which testosterone has been suggested, has not been subjected to adequate trials, to justify androgenic therapy other than on an experimental basis.’ No ‘noticeable improvement’ in mental condition was found in 5 cases of male involutional melancholia who were treated with intramuscular injections of testosterone propionate 10mg 3 times weekly for a period of 3 to 4 weeks by Barahal (1938). Barahal (1940) also found little or no change in the mental condition of 7 psychotic male homosexual patients who were treated with intramuscular injection of testosterone propionate (25mg) 3 times weekly for 18 months. In addition, Pardoll and Belinson (1941) reported that mental improvement was not sufficiently pronounced to warrant administering testosterone propionate as routine treatment for the male involutional psychoses after treating 11 males with 10mg doses of testosterone propionate twice weekly for 3 months and observing behaviour for 2 months following cessation of therapy.

People that started using steroids as teenagers are also prone to violent outburst as the introduction of steroids during puberty significantly alters the chemical pathways in the brain.  Studies have documented that teenagers that use steroids show that the neurological pathways in the brain are highly vulnerable to damage.  Steroids interfere with the brains ability to produce serotonin.  Serotonin is what gives us our sense of well being.  When the production of serotonin is interfered with it usually leads to increased depression as well as aggression and frequently these are permanent.  Which means even if you stop using steroids “whats done is done” you can’t go back.
In young  women that use steroids you’re messing with a hormone balance that is already delicate which can only mean trouble.  Steroids significantly reduce your levels of estrogen and progesterone leading leading to both short term and long term effects including severe depression and anxiety.  Women and teenage girls that use steroids that disrupt the delicate balance between the female hormones estrogen and progesterone also run the risk of not just temporary infertility but permanent infertility as well as the severe anxiety and depression .  The depression can be severe enough to lead to suicide in both men and women.  Another potential side effect related to long term steroid use is addiction, and not just addiction to steroids but to other drugs as well ranging from caffeine to benzodiazapines and even to drugs like cocaine and heroine which are already highly addictive.  Testosterone interferes with the dopamine antagonists in the brain which are responsible for limiting the effects of drug use and inhibiting your desire for more.  For example, say you always had just one cup of coffee in the morning and no desire for more, with long term steroid use you would start wanting/needing a second and a third etc.
Though there is no guarantee that you will experience long term and/or psychological effects from steroid use the chances that you will are significantly higher than that you won’t.  Most side effects of steroid use are related to dose and the length of time you take steroids.  Also, the earlier you start using steroids has a significant impact.  Teenagers that use steroids especially during puberty even if they stop in early adulthood have already caused irreversible damage in many ways.  If you are considering steroid use first of all don’t forget they’re illegal for a reason.  they are dangerous and should be used with extreme caution.  Research, research, research, and I don’t mean in the locker room or in a chat room and whatever you do do not skip over the section of side effects.  Read ALL the side effects and think about them.  They may not develop for several years but chances are they will develop and it will be too late to change your mind.

I can also tell you that with this compounds, you really need ALL of the standard AI and SERMs possibly even cabor. and your pcts. These can effect your mood by a stagering ammount as they do what we all know they do and help us with nast estro problems. Get your blood work. Start with test E. Do bloods to see the result and you have a good base to introduce new compounds to the mix. Its very interesting, this, learning about your body buisness AND can make you feel like a god. (not just with tren. you gotta dial in that sweet spot for each compound as your body accepts)
Hope you find something that works

Steroid effects on mental health

steroid effects on mental health

People that started using steroids as teenagers are also prone to violent outburst as the introduction of steroids during puberty significantly alters the chemical pathways in the brain.  Studies have documented that teenagers that use steroids show that the neurological pathways in the brain are highly vulnerable to damage.  Steroids interfere with the brains ability to produce serotonin.  Serotonin is what gives us our sense of well being.  When the production of serotonin is interfered with it usually leads to increased depression as well as aggression and frequently these are permanent.  Which means even if you stop using steroids “whats done is done” you can’t go back.
In young  women that use steroids you’re messing with a hormone balance that is already delicate which can only mean trouble.  Steroids significantly reduce your levels of estrogen and progesterone leading leading to both short term and long term effects including severe depression and anxiety.  Women and teenage girls that use steroids that disrupt the delicate balance between the female hormones estrogen and progesterone also run the risk of not just temporary infertility but permanent infertility as well as the severe anxiety and depression .  The depression can be severe enough to lead to suicide in both men and women.  Another potential side effect related to long term steroid use is addiction, and not just addiction to steroids but to other drugs as well ranging from caffeine to benzodiazapines and even to drugs like cocaine and heroine which are already highly addictive.  Testosterone interferes with the dopamine antagonists in the brain which are responsible for limiting the effects of drug use and inhibiting your desire for more.  For example, say you always had just one cup of coffee in the morning and no desire for more, with long term steroid use you would start wanting/needing a second and a third etc.
Though there is no guarantee that you will experience long term and/or psychological effects from steroid use the chances that you will are significantly higher than that you won’t.  Most side effects of steroid use are related to dose and the length of time you take steroids.  Also, the earlier you start using steroids has a significant impact.  Teenagers that use steroids especially during puberty even if they stop in early adulthood have already caused irreversible damage in many ways.  If you are considering steroid use first of all don’t forget they’re illegal for a reason.  they are dangerous and should be used with extreme caution.  Research, research, research, and I don’t mean in the locker room or in a chat room and whatever you do do not skip over the section of side effects.  Read ALL the side effects and think about them.  They may not develop for several years but chances are they will develop and it will be too late to change your mind.

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