This form if injection is used in treating many skin conditions including acne lesions, cysts, alopecia (bald spots), eczema , abundant scar tissue (keloids, hypertrophic scars), psoriasis , lichen simplex chronicus, skin lupus, granuloma annulare, and more. Intralesional injections are extremely helpful, as they are able to bypass the outer defensive layers of the skin to reach an area that will make the greatest impact on your condition. It is common for a patient to need multiple injections, as different cases vary in severity.
Twenty-seven studies enrolling 1325 patients were included. Quality of evidence was generally low. Good to excellent size reduction was reported in 84 percent of lymphatic and 87 percent of venous malformations. Pulmonary fibrosis was never encountered. Meta-analysis of four studies on venous malformations treated with bleomycin versus other sclerosants showed similar size reduction (OR, ; 95 percent CI, to ) but a significantly lower adverse event rate (OR, ; 95 percent CI, to ) and fewer severe complications after bleomycin. Symptom relief, quality of life, and patient satisfaction were reported inadequately.