The molecular makeup of aromatase inhibitors operate through an irreversible death bond, giving them the name ?suicide inhibitors?, however, these oral aids have lacked the hearty half-life needed for all day lock down on aromatase activity. This leaves testosterone a sitting duck for the feminizing fiend within a few hours. This anti-fem flaw is largely due to the digestive route that oral compounds are filtered; mouth, stomach, small intestines-then sorted as fat, or no fat. Most meds are fat free and routed through capillaries to the liver where first pass metabolism reduces them to a fraction of original efficacy. Fats are sorted into the lymphatic system where they travel to the heart and pumped through systemic circulation before reaching the overzealous metabolic machine of the liver. This increased time spent in circulation is key to extending bioavailability of oral meds.