Many users have reported negative effects on the kidneys. However, there is no accurate evidence of this. Perhaps this theory appeared due to the fact that, while using Trenbolone, the urine becomes much darker. But there is an explanation for this: since Trenbolone suffers little to no breakdown, the compound is excreted in the urine in a rusty, oxidised form. Researches tend to demonstrate that kidney damages are actually due to the increased water loss and sweating while using Trenbolone. This is why Trenbolone users are advised to keep high the water intake.